MOTS-c – 40mg

Mitochondrial-Derived Peptide for Metabolic and Energy Regulation Research | From Peptide Research Hub

What is MOTS-c?

MOTS-c is a mitochondrial-derived peptide that has gained significant attention in research involving metabolism, energy utilization, and cellular adaptation to stress. Unlike many peptides that originate from nuclear DNA expression, MOTS-c is encoded within mitochondrial DNA, giving it a unique role in the study of mitochondrial signaling and metabolic regulation.

Researchers investigate MOTS-c for its potential involvement in glucose handling, insulin sensitivity, exercise response, and age-related metabolic decline. Because mitochondria play such a central role in energy production, cellular respiration, and oxidative balance, MOTS-c is often explored in models related to obesity, endurance, and metabolic resilience.

The 40mg format provides a higher-yield option for laboratories conducting extended protocols or comparative metabolic studies involving mitochondrial function and peptide signaling.

Mechanism of Action

MOTS-c is believed to regulate metabolic homeostasis by influencing nuclear gene expression in response to mitochondrial stress. It has been studied for its ability to activate pathways related to glucose uptake, AMP-activated protein kinase (AMPK), and cellular energy efficiency.

In research settings, MOTS-c is often associated with improved metabolic flexibility and adaptive stress responses. This includes investigations into how cells shift fuel usage under conditions of nutrient challenge, exercise demand, or mitochondrial dysfunction. Its role in mitochondrial-to-nuclear communication makes it a compelling peptide for researchers seeking to better understand how cells maintain balance under metabolic pressure.

Because of these properties, MOTS-c is widely studied in models involving endurance, insulin response, obesity, and healthy aging.

Research Applications

• Metabolic function and glucose regulation studies
• Mitochondrial signaling and cellular stress research
• Energy balance and exercise adaptation models
• Insulin sensitivity and metabolic flexibility investigations
• Obesity and age-related metabolic decline research
• AMPK activation and mitochondrial communication studies

Why Choose PRH?

• ≥99% purity peptides (HPLC-verified)
• Reliable batch consistency for research accuracy
• Trusted peptide source with 15+ years experience

Product Specifications

• Compound: MOTS-c
• Concentration: 40mg per vial
• Form: Lyophilized peptide powder
• Purity: ≥99% (HPLC-tested)
• Appearance: White to off-white powder
• Storage: -20°C; refrigerate after reconstitution
• Solvent: Bacteriostatic water recommended

Disclaimer: This product is intended for research and laboratory use only. Not for human or veterinary use.